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Researcher
Anton Roebroek
- Disciplines:Genetics, Systems biology, Medical imaging and therapy, Molecular and cell biology, Other paramedical sciences
Affiliations
- Department of Human Genetics (Department)
Member
From1 Oct 1999 → Today
Projects
1 - 5 of 5
- The Role of LRP1 in Tumor Growth and Metastasis.From1 Sep 2011 → 8 Oct 2018Funding: IWT personal funding - strategic basic research grants
- The relevance of LRP1 in the metabolism of Abeta, the major component of senile plaques in Alzheimer's disease.From1 Jan 2011 → 31 Dec 2014Funding: FWO research project
- The role of the ApoE receptor LRP1 in processes relevant for the development of the metabolic syndrome.From1 Jan 2010 → 31 Dec 2013Funding: FWO research project
- The role of LRP1 als modulator of the activity of (pro-)heparanase-1 in tumor growth and metastasis.From1 Jan 2008 → 31 Dec 2011Funding: FWO research project
- LRP1 as modulator of the activity of heparanase-1: impact on tumor growthand metastasis.From1 Jan 2008 → 1 Dec 2010Funding: IWT personal funding - strategic basic research grants
Publications
1 - 10 of 27
- Pathogenic Aβ production by heterozygous PSEN1 mutations is intrinsic to the mutant protein and not mediated by conformational hindrance of wild-type PSEN1(2023)
Authors: Anton Roebroek
- Syntenin-knock out reduces exosome turnover and viral transduction(2021)
Authors: Rudra Shankar Kashyap, Anton Roebroek, Guido David, Pascale Zimmermann
- Mutation in the distal NPxY motif of LRP1 alleviates dietary cholesterol-induced dyslipidemia and tissue inflammation(2021)
Authors: Anton Roebroek
- LRP1 Has a Predominant Role in Production over Clearance of Aβ in a Mouse Model of Alzheimer's Disease(2019)
Authors: Anton Roebroek
Pages: 7234 - 7245 - Single mild traumatic brain injury results in transiently impaired spatial long-term memory and altered search strategies(2019)
Authors: An Schreurs, Anton Roebroek, Detlef Balschun
- The Matricellular Receptor LRP1 Forms an Interface for Signaling and Endocytosis in Modulation of the Extracellular Tumor Environment(2015)
Authors: Bart Van Gool, Anton Roebroek
Pages: 1 - 9 - Hematopoietic Stem/Progenitor Cells Directly Contribute to Arteriosclerotic Progression Via Integrin Β2(2015)
Authors: Anton Roebroek, Paul P Van Veldhoven, Catherine Verfaillie, Yingmei Feng
Pages: 1230 - 1240 - Hematopoietic Stem/Progenitor Cells Directly Contribute to Arteriosclerotic Progression via Integrin beta(2)(2015)
Authors: Anton Roebroek, Paul P Van Veldhoven, Catherine Verfaillie
Pages: 1230 - 1240 - Generation of an Allelic Series of Knock-In Mice Using Recombinase-Mediated Cassette Exchange (RMCE)(2014)
Authors: Anton Roebroek, Bart Van Gool
Pages: 63 - 76 - LRP1 is critical for the surface distribution and internalization of the NR2B NMDA receptor subtype(2013)
Authors: Anton Roebroek
Pages: 25