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Patent

Glycosylation of variable immunoglobulin domains

The present invention provides nucleotide sequences encoding polypeptides comprising immunoglobulin variable domains with engineered glycosylation acceptor sites. Specifically, the invention provides immunoglobulin variable domain proteins modified with selected glycans and specific glycan-conjugates thereof. Also provided herein are methods for the production of glycosylated immunoglobulin variable domains and glycan-conjugates thereof.
Patent Publication Number: WO2018206734
Year filing: 2018
Year approval: 2019
Year publication: 2018
Status: Requested
Technology domains: Biotechnology
Validated for IOF-key: Yes
Attributed to: Associatie Universiteit Gent