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Patent

Improved aminopeptidases for single molecule peptide sequencing

The present invention relates to protein sequencing, more particularly the invention discloses improved aminopeptidases for single molecule protein sequencing and/or amino acid identification. Said aminopeptidases can enzymatically cleave off N-terminal amino acids and are highly suitable in a kinetics-based peptide sequencing approach. Based on the kinetics of the cleaving reaction or of the engagement between said aminopeptidases and peptide to be sequenced, information on the identity of the cleaved amino acids is provided.
Patent Publication Number: WO2021116163
Year filing: 2021
Year approval: 2022
Year publication: 2021
Status: Requested
Technology domains: undefined
Validated for IOF-key: Yes
Attributed to: Associatie Universiteit Gent