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Patent

Genetically engineered eukaryotic cells producing sialylated glycoproteins

The present application provides glycosylation engineered higher eukaryotic cells which produce homogeneous forms of sialylated glycans present on a recombinant glycoprotein. In particular, the glycosylation engineered higher eukaryotic cells produce homogeneous forms of small N- glycan structures which carry terminal sialic acid residues. In addition, the invention provides glycan-conjugates based on specific coupling with sialic acid residues present on the recombinant glycoproteins.
Patent Publication Number: EP3682018
Year filing: 2020
Year approval: 2021
Year publication: 2020
Status: Requested
Technology domains: Pharmaceuticals
Validated for IOF-key: Yes
Attributed to: Associatie Universiteit Gent