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Chapter 2 : host polymorphisms and COVID-19 infection

Journal Contribution - Journal Article

Abstract Coronavirus disease (COVID-19) is an infectious disease caused by a newly discovered coronavirus, severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). There is growing evidence that host genetics play an important role in COVID-19 severity. Based on current knowledge about the human protein machinery for SARS-CoV-2 entry, the host innate immune response, and virus-host interactions, the potential effects of human genetic polymorphisms, which may contribute to clinical differences in SARS-CoV-2 pathogenesis, may help to determine the individual risk for COVID-19 infection and outcome.
Journal: ADVANCES IN CLINICAL CHEMISTRY
ISSN: 2162-9471
Volume: 107
Pages: 41 - 77
Accessibility:Closed