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Infrastructure

3D SUper-Resolution to cryo-Electron MIcroscopy to study nanoscale subcellular dynamics and structure that alter in Neurodegenerative Diseases - 3SURE MIND (3SURE MIND)

The infrastructure includes a new super-resolution microscope, which can visualize processes inside the cell using light microscopy at a much higher resolution than what is currently available. The microscope also integrates a laser that can mark areas in the investigated samples, allowing to examine these samples by electron microscopy (reaching even higher resolution), and thus easily connect areas of interest across platforms. To further facilitate this, a new cryo-stage is added to one of our electron microscopes

Type: Equipment
Location type: Single sited
Accessibility: Researchers knowledge institutions
In use: 31 Oct 2022 →  Today
Disciplines: Intracellular compartments and transport, Neurological and neuromuscular diseases, Membrane structure and transport, Structural biology
Keywords: Correlative Super-resolution to EM, Membrane contact sites, Endolysosomal homeostasis, amyloid