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Cell Biology and Histology Vrije Universiteit Brussel

The Department of Cell Biology (CYTO-VUB) is specialized in molecular and cellular liver research, with a main focus on the (patho)biology of hepatic stellate cells and liver progenitor cells. Prof. A. Geerts contributed to the first paper on isolation, purification and culturing of hepatic stellate cells (1) and is the author of a side scatter activated cell sorting method to purify freshly isolated hepatic stellate cell up to 95 - 100% (2). ...

Natural Products and Food - Research and Analysis (NatuRA) University of Antwerp

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The consortium on Natural Products & Food Research and Analysis has a unique expertise in Flanders in the areas of: (1) method development and validation for quality control of herbal medicinal products and food supplements, (2) fundamental research on medicinal plants, (3) identification of biologically active compounds in food and (4) active drug metabolite profiling. NatuRA combines the complementary expertise of three research teams at ...

Toxicology, Dermato-cosmetology and Pharmacognosy Vrije Universiteit Brussel

Topic A: Experimental in vitro toxicology: The use of isolated hepatocytes and their cultures for pharmaco- toxicological studies with focus on phase I and phase II biotransformation of xenobiotics; liver zonation of xenobiotic transformation; cell cycle and molecules affecting cell progression and cell signaling; the role of apoptosis in cell cultures; connexins and their importance in cell signaling. Topic B: Dermato-Cosmetic Sciences: ...

Experimental in vitro toxicology and dermato-cosmetology Vrije Universiteit Brussel

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The In Vitro Toxicology and Dermato-cosmetology (IVTD) research group of the Vrije Universiteit Brussel (VUB) constitutes a hub for many promising R&D projects within a broad scientific scope. They all share one common goal, namely an improvement of human health and safety. We achieve this by:

  • Developing robust and human-relevant liver-based in vitro models to discriminate between safe and toxic drug candidates, and ...

Pharmaceutical and Pharmacological Sciences Vrije Universiteit Brussel

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The department FAFY is mainly developing research activities in the following domains: 1. The use of hepatocytes in culture and co-culture as a model for toxicity and biotransformation studies of xenobiotics: - Evaluation of the iso-enzyme pattern of hepatocytes in culture and co-culture; - Detoxification mechanisms of hepatocytes in cultures and co-cultures; - Biotransformation and toxicity of isobutene; - Biotransformation and toxicity of ...

Laboratory of Angiogenesis and Vascular Metabolism (VIB-KU Leuven Center for Cancer Biology) KU Leuven

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The research group of the Laboratory of Angiogenesis and Neurovascular Link focuses on a central theme, i.e. unraveling the molecular basis of angiogenesis (i.e. the formation of blood vessels) and translating these genetic insights in therapeutic concepts – and, if possible, novel treatments. The group has also broadened its scope of interest to the exciting research avenue of the neurovascular link, illustrating that vessels and nerves have ...

Laboratory of Molecullar and Cellular Therapy Vrije Universiteit Brussel

The focus of the LMCT is directed towards the application of basic immunological knowledge and molecular biotechnology for the understanding, diagnosis and treatment of human diseases, in particular haematological malignancies and solid tumors. Molecular techniques and tools developed in a research setting are made available for the diagnosis and the follow-up of patients. Studies in pre- clinical animal models are performed with the aim to ...

Proteinchemistry, proteomics and epigenetic signalling(PPES) University of Antwerp

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The cluster Proteinscience, proteomics and epigenetic signalling is active on three domains: neurodegeneration, infection and inflammation. For the first part the cluster studies for example the effects of hypoxia/ischemia and the role of hemeproteins herein and how this is perceived in metabolic active tissue such as brain. In the second part the virus-ghost relationship will be studie on intra- and extracellulair level. In the final part the ...