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Human molecular genetics University of Antwerp

The main research interest lies in the field of sensory genetics. Although work is done for different forms of sensory diseases, the emphasis is on nonsyndromic sensorineural hearing impairment and otosclerosis. Large families are collected in Belgium and The Netherlands, as well as in countries with high consanguinity rate such as Iran. These pedigrees are analyzed by linkage analysis. Subsequently, the genes involved are identified by ...

Laboratory for Complex Genetics KU Leuven

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The Laboratory for Complex Genetics works on the genetics of complex (multifactorial) disease, with a special focus on neurodegenerative disorders (Alzheimer’s disease), and inflammatory bowel disease (IBD). We employ a translational genetics approach in the context of specific clinical questions: (early) diagnosis, disease subtypes, disease progression, therapy options... Specifically we use data from large-scale genomic datasets (genotyping ...

Laboratory for Experimental Mouse Genetics KU Leuven

The research of the Laboratory for Experimental Mouse Genetics is focused upon the study of the function of the multifunctional cell surface receptor, lipoprotein receptor-related protein 1 (LRP1). Via a novel application of recombinase-mediated cassette exchange (RMCE) multiple knock-in mutation were generated in this receptor, especially in the intracellular domain of this receptor, effecting the interaction of the receptor with ...

Laboratory for Genetics of Cognition KU Leuven

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Research in the Laboratory for Genetics of Cognition focuses on the clinical, genetic and molecular characterization of genetic disorders, associated with intellectual disability, X-linked as well as autosmal. Besides gene identification, applying the latest technology, we are also involved in developing models for neurodevelopmental disorders using the induced pluripotent stem cell technology.

Laboratory for Genetics of Human Development KU Leuven

The research in the Laboratory for Genetics of Human Development has a focus on the clinical and genetic characterisation of genetic disorders, with special emphasis on dysmorphology, congenital malformations of the heart and face and intellectual disability. They contribute to the ongoing definition of novel clinical entities and to the further delineation of existing syndromes.

Laboratory for Genetics of Malignant Disorders KU Leuven

The discovery and functional characterization of new, recurrent cytogenetic or molecular aberrations in malignant disorders are the most important research objectives of the laboratory for Genetics of Malignant Disorders. These research objectives connect almost seamlessly with the diagnostic, cytogenetic and molecular services which CME-UZ offers for nearly each malignant pathology: acute and chronic leukaemia, lymphomas, mesenchymal and ...

Laboratory for Human Evolutionary Genetics KU Leuven

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Our research group is interested in human evolution and evolutionary population genetics in the broadest sense. We work on questions relating global genetic population structure with evolutionary processes such as selection, drift, migrations and admixture. We use evidence from modern and ancient genomes to study genetic changes taking place over time and space.

Laboratory for Imaging Genetics KU Leuven

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Medical Imaging Research Center is part of the department of human genetics of the KU Leuven. The Medical Imaging Research Center (MIRC) is an interdisciplinary research center with a central location in the University Hospital Gasthuisberg. It is surrounded by the different clinical imaging departments yielding easy access to the state-of-the-art imaging equipment and patient data. The focus lies on fundamental and translational research in ...

Laboratory of Behavioral and Developmental Genetics KU Leuven

The Laboratory of Behavioral and Developmental Genetics researches Gene circuits in Drosophila brain development as models for human neurodevelopmental disorders from transcription factors to effector genes and signaling pathways.

The long-term objectives of their research comprise:

  • the determination of the complexity of gene circuits required for neuronal identity and connectivity,
  • the analysis of the relationship ...