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Neurogenetics Group University of Antwerp
Many neurodegenerative disorders have a genetic etiology or are complex disorders caused by an interaction between environmental and inherited factors. In our research group we focus on the clinical and genetic aspects of inherited peripheral neuropathies and inherited epilepsy syndromes. The clinical, electrophysiological and neuropathological characterization of patients affected by these disorders forms the starting point for molecular ...
Chris Delgado Ratto University of Antwerp
VIB CMN - Genetics of Alzheimer’s Disease University of Antwerp
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The research unit is committed to increase insight in the complex genetics of Alzheimer's disease and to investigate the translational potential of genetic discovery. We use genetic-epidemiological methods and advanced genomic technologies to identify molecular mechanisms that can serve as future targets for early detection, prevention and treatment. Techniques include 2nd and 3rd generation DNA and RNA sequencing on various biomaterials, ...
Alexander Neumann Flanders Institute for Biotechnology University of Antwerp
Rita Cacace Flanders Institute for Biotechnology University of Antwerp
Department of Embryology and Genetics Vrije Universiteit Brussel
The Research Department of Embryology and Genetics (EMGE) is linked to the Centres for Medical Genetics and Reproductive Medicine and the Department of Paediatrics of the UZ Brussel and consists of several research clusters. Historically, the group has been interested in metabolic diseases such as lysosomal storage diseases and this has led to the close collaboration with the neuro-paediatricians of the hospital, investigating mitochondrial ...
Cell Genetics Vrije Universiteit Brussel
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The laboratory for Cell Genetics (Cytogenetics) studies variation in genotype and phenotype, cell division pathways, cell death and genetic changes relevant for the increase of cancer in human. Genotoxicity tests assess the induction of DNA damage, gene mutations, structural and numerical chromosome aberrations. Their predictivity for cancer induction is supported by international studies relating mutations and activation of cancer related ...
Medical genetics of obesity and skeletal disorders (MGENOS) University of Antwerp
The general aim of the research is to identify genes that are relevant for two multifactorial conditions, osteoporosis and obesity, in order to understand the pathogenesis of these conditions and to reveal novel putative therapeutic targets. In order to obtain this, the specific aims of our work are: - identification of genes for monogenic conditions with an abnormal bone density - identification of genes involved in rat models with an increased ...
Applied Molecular Genomics University of Antwerp
Psychiatric disorders, such as major depression or unipolar disorder (UP), manic depression or bipolar disorder (BP) and schizophrenia, are among the most frequent brain diseases worldwide. An estimated 9-10% of the world population suffers from major depression, while bipolar disorder and schizophrenia each affect ~1% of the population. Although the precise causes of psychiatric diseases are still largely unknown, family studies argue for a ...