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Our scientific interests are to reveal how membrane-associated scaffold proteins and lipids participate in cell signaling and multicellular organization/homeostasis. We provided major contributions to our understanding of the importance of membrane trafficking for the biology of heparan sulfate proteoglycans, the role of phospholipids in the function of PDZ proteins and more recently the molecular mechanisms of exosome biogenesis. Our current ...

HEIM is part of the Oncology Research Center and consists of a fundamental research team located at the Faculty of the Brussels Health Campus and a translational research team located at the University Hospital. Fundamental Research consists of cancer research in different tumor models including Multiple Myeloma, Acute Myeloid Leukemia and B-cell lymphoma. The aim of this research is to find novel therapeutic targets within the field of ...