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Laboratory of Biosignaling & Therapeutics KU Leuven

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The Laboratory of Biosignaling & Therapeutics investigate cellular signal transduction pathways at the molecular level. One of our major goals is to identify and develop novel biomarkers or therapeutic targets for human diseases. The current focus is on the (mis)regulation of chromatin signaling, DNA repair and cell division in cancer cells by enzymes known as protein phosphatases.

Medicinal Chemistry (UAMC) University of Antwerp

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The research topics in the Department of Medicinal Chemistry deal with the development of new medicines and focus mainly on following topics: 1. The investigation of enzymes as target for the design of biologically active compounds. Making use of the substrate selectivity of the enzyme, inhibitors are developed. Various medicinal chemical strategies and 'in silico' chemistry are used. These inhibitors are synthetized and chemically ...