The focus of the Laboratory for Molecular and Cellular Therapy (LMCT) is directed towards the application of basic immunological knowledge and molecular biotechnology for the understanding, diagnosis and treatment of human diseases, including cancer, infectious disease and brain disease.
Convincing evidence continues to emerge from clinical trials that gene therapy is yielding therapeutic effects in patients suffering from a wide range of diseases. Moreover. the use of adult stem cells and the reprogramming of cells towards pluripotency are being heralded as some of the most promising developments in regenerative medicine at the forefront of medical innovation. This mirrors worldwide efforts in some of the leading research ...
The division Molecular Virology and Gene Therapy aims at developing novel therapeutics and diagnostics starting from basic research into the molecular cause of disease and employing the most advanced biomedical technologies. Research can be basic, applied or technological; in all cases our research aims at future applications in medicine.
Major disease areas are AIDS and Parkinson's disease. Other interests are gene therapy of cystic ...
The Laboratory of Cell Death Research & Therapy researches Defective regulation of cell death, especially in the form of apoptosis, contributes to the development of crucial pathologies including cancer and plays a major role in chemoresistance. Mechanisms regulating cancer cell death also affect the emission of ‘danger signals’ from the stressed/dying cells, which critically define their ‘immunogenic character’ and impact the initiation ...
The Radiofarmaceutical Research team aims to develop and apply new radiopharmaceuticals for diagnosis (PET en SPECT) or for radionuclide therapy. The development of radiopharamaceuticals can be subdivided in different steps in which the team has acquired expertise:
The discovery and functional characterization of new, recurrent cytogenetic or molecular aberrations in malignant disorders are the most important research objectives of the laboratory for Genetics of Malignant Disorders. These research objectives connect almost seamlessly with the diagnostic, cytogenetic and molecular services which CME-UZ offers for nearly each malignant pathology: acute and chronic leukaemia, lymphomas, mesenchymal and ...