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Therapeutic and Diagnostic Antibodies KU Leuven

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Since over 25 years the laboratory focusses on the generation and characterization of monoclonal antibodies (Mabs), antibody derivatives, nanobodies and diabodies and application as either therapeutics, diagnostics or research tools.

Major research lines include:

  • Studies on structure-function relationship in proteins involved in cardiovascular disease (e.g. Plasminogen Activator inhibitor-1 (PAI-1) and Thrombin Activatable ...

Physiopharmacology (PHYSPHAR) University of Antwerp

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The research of the Laboratory of Physiopharmacology is focused on the cardiovascular system. A first line of research involves the morphological and haemodynamic changes that occur during the development and rupture of atherosclerotic plaques. Various experimental models have been established in rabbits and in genetically modified mice. Recently, we developed for the first time a model of atherosclerosclerotic plaque rupture in mice with ...