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Laboratory of Protein Phosphorylation and Proteomics KU Leuven

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  • We investigate the regulation of (patho)physiological processes via reversible protein phosphorylation, and explore the therapeutic potential of the kinases and phosphatases involved. Focus is on Protein Kinase D (PKD) and Protein Phosphatase 2A (PP2A), but increasingly also on broader (kinome and phosphatome wide) approaches to systematically identify kinases/phosphatases that are implicated in (patho)physiological ...

Laboratory of Biosignaling & Therapeutics KU Leuven

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The Laboratory of Biosignaling & Therapeutics investigate cellular signal transduction pathways at the molecular level. One of our major goals is to identify and develop novel biomarkers or therapeutic targets for human diseases. The current focus is on the (mis)regulation of chromatin signaling, DNA repair and cell division in cancer cells by enzymes known as protein phosphatases.