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VIB CMN - Neurodegenerative Brain Diseases Group University of Antwerp

Our focus is on genetics, genomics and neuropathology of the neurodegenerative brain diseases Alzheimer's disease (AD), frontal temporal lobar degeneration (FTLD) and Parkinson's disease (PD), attempting to find molecular mechanisms of protein aggregation in dementia. We systematical collect large samples of patients and relatives for genetic studies aiming at identifying disease genes using either a positional cloning strategy in multiplex ...

Laboratory for the Research of Neurodegenerative Diseases (VIB-KU Leuven) KU Leuven

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The Laboratory for the Research of Neurodegenerative Diseases performes research into the fundamental molecular processes that underlay neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Their work has also contributed to insights into general physiologically mechanisms, in particular, the understanding of regulated intramembrane proteolysis as an important signaling mechanism in health and disease. They have demonstrated the ...

Laboratory of Neurophysiology in Neurodegenerative Disorders (VIB- KU Leuven) KU Leuven

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Neuronal and neurodegenerative disorders are extremely debilitating conditions, affecting millions of people worldwide. For most of these diseases, there are no cures and only symptomatic treatments exist. We are working hard to understand the mechanistic basis of these diseases with the ultimate hope to find cures.

We have uncovered exciting new avenues in the context of Alzheimer’s disease, Parkinson’s disease, ALS and dystonia and ...

VIB CMN - Genetics of Alzheimer’s Disease University of Antwerp

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The research unit is committed to increase insight in the complex genetics of Alzheimer's disease and to investigate the translational potential of genetic discovery. We use genetic-epidemiological methods and advanced genomic technologies to identify molecular mechanisms that can serve as future targets for early detection, prevention and treatment. Techniques include 2nd and 3rd generation DNA and RNA sequencing on various biomaterials, ...

Laboratory of Sleep and Synaptic Plasticity (VIB-KU Leuven) KU Leuven

Responsible

The computational processes of the brain that direct behavior are only possible because of trillions of synaptic connections between billions of neurons and the connections of the brain to the outside world. We try to elucidate how these connections are established and what is the underlying code of synaptic specificity, stability, plasticity and function.

The questions we tackle are how glial support plays a crucial role, how the ...