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We are interested in generating a quantitative understanding of the molecular mechanisms underlying Alzheimer’s disease pathogenicity. Our research is based on the premise that getting a better mechanistic understanding of the function of the molecules involved in familial Alzheimer’s disease (FAD) will offer critical insights into the molecular basis of the disease and open new research avenues leading to innovative and safe strategies to ...

The Laboratory for the Research of Neurodegenerative Diseases performes research into the fundamental molecular processes that underlay neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Their work has also contributed to insights into general physiologically mechanisms, in particular, the understanding of regulated intramembrane proteolysis as an important signaling mechanism in health and disease. They have demonstrated the ...

Neuronal and neurodegenerative disorders are extremely debilitating conditions, affecting millions of people worldwide. For most of these diseases, there are no cures and only symptomatic treatments exist. We are working hard to understand the mechanistic basis of these diseases with the ultimate hope to find cures.

We have uncovered exciting new avenues in the context of Alzheimer’s disease, Parkinson’s disease, ALS and dystonia and ...