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Laboratory for Molecular Diagnosis KU Leuven

Responsible

The translational research activities of the diagnostic team concern the development and validation of new technologies for use in diagnostics. The lab has developed specific gene panels for various genetically heterogeneous disorders and offers 'mendelioom' sequencing within the clinical service.

Molecular Digestive Oncology KU Leuven

Responsible

The laboratory for Molecular Digestive Oncology focusses on gastro-intestinal cancers and currently has two types of activities:

  • large molecular annotation projects, aimed at better describing the overall molecular identity of GI tumors and potential subtypes. Activities here include in depth molecular annotation of tumor series, state of the art bioinformatics for subtype derivation and biological annotation, comparisons of ...

Laboratory of Molecular Biology of Leukemia (VIB-KU Leuven) KU Leuven

Responsible

The Laboratory of Molecular Biology of Leukemia tries to understand the genetic complexity of leukemia, with the aim to use that information to develop novel treatment strategies.

Leukemia is a genetically complex disease that is characterized by the accumulation of abnormal blood cells. The leukemia cells often harbor chromosomal defects and additional more sublte changes (mutations) in their genome. This information is used for ...

Molecular Parasitology Institute of Tropical Medicine

Introduction

MPU explored the diversity of Leishmania and leishmaniases for over 25 years, ‘from genomes to eco-systems’. As such, we have developed a relevant laboratory experience in (i) parasitology and (ii) molecular biology both in the high-tech context of a modern lab and in the working conditions of a laboratory in a tropical context.

Since 2002, the unit is headed by Jean-Claude Dujardin, zoologist (Facultés Notre Dame ...

Molecular biophysics, physiology and pharmacology University of Antwerp

The laboratory for molecular biophysics, physiology and pharmacology studies the underlying mechanisms of the excitability of the heart or nervous system. The electrical activity is regulated by ionic currents passing the plasmamembrane, originating from the opening and closing of ion channels. The determination of the molecular architecture, the modulation by external factors or drugs, the elucidation of the structure function relationship as ...

VIB CMN - Molecular Neurogenomics University of Antwerp

Responsible
The Lab focuses on the identification and characterization of disease-causing genes and pathways implicated in the molecular etiology of neurological disorders, like inherited peripheral neuropathies (CMT) and inherited epilepsies. For this purpose we use two major research strategies: - unraveling the role of aminoacyl-tRNA synthetases in peripheral neurodegeneration as a tool for understanding the molecular pathomechanisms of peripheral ...

Department of Cellular and Molecular Medicine KU Leuven

Responsible

For more information about the research topics of the different research teams belonging to this department see: - Division for Biochemistry - Division for Physiology - Division for Pharmacology - Centre for Human Genetics - Division for Experimental laboratory medicine - Division for Molecular Biology (CELGEN)

Molecular Virology and Gene Therapy KU Leuven

Responsible

The division Molecular Virology and Gene Therapy aims at developing novel therapeutics and diagnostics starting from basic research into the molecular cause of disease and employing the most advanced biomedical technologies. Research can be basic, applied or technological; in all cases our research aims at future applications in medicine.
Major disease areas are AIDS and Parkinson's disease. Other interests are gene therapy of cystic ...

Centre for Molecular and Vascular Biology KU Leuven

Responsible

The Center for Molecular and Vascular Biology performs research related to the following topics:- Pathogenesis of thrombosis and bleeding. - Development of assays for the diagnosis of thrombosis and bleeding. – Signalling and transcription factor regulation in megakaryocytes and platelets. - Genetics for bleeding and thrombotic disorders. –(patho)physiology of megakaryopoiesis. – Role of transcription factors in endothelial heterogeneity. – ...