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The Laboratory of Lipid Metabolism and Cancer focusses on altered lipid metabolism in cancer cells. Using a state-of-the-art mass spectrometry-based lipidomics technology the group has made the intriguing observation that development and progression of cancer is almost invariably accompanied by dramatic changes in the cell’s composition of phospholipids. As phospholipids play a key role in the formation of membranes, which organize numerous ...

The Laboratory of Lipid Biochemistry and Protein Interactions conducts high quality fundamental research, focusing on the role of peroxisomes in complex cellular processes (lipid metabolism, ROS/RNS metabolism, organelle dynamics and dysfunctions) in mammals and aims to provide insight in inherited and other human disorders linked to these organelles via cellular studies and mouse models.

The Laboratory of Lipid Biochemistry and Protein ...

Our scientific interests are to reveal how membrane-associated scaffold proteins and lipids participate in cell signaling and multicellular organization/homeostasis. We provided major contributions to our understanding of the importance of membrane trafficking for the biology of heparan sulfate proteoglycans, the role of phospholipids in the function of PDZ proteins and more recently the molecular mechanisms of exosome biogenesis. Our current ...