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Laboratory of Virology and Chemotherapy (Rega Institute) KU Leuven

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This unit designs and develops antiviral and antitumor agents, primarily nucleoside, nucleotide or oligonucleotide analogues but also other substances which interact with enzymes involved in nucleic acid metabolism (i.e. DNA polymerase, reverse transcriptase, thymidine kinase, thymidylate kinase, nucleoside phosphorylase, dihydropyrimidine dehydrogenase, adenosine deaminase, S-adenosylhomocysteine hydrolase, IMP dehydrogenase, OMP ...