The Laboratory of Synapse Biology aims to unravel the molecular mechanisms that control neuronal connectivity in developing circuits, and determine how perturbations in this process affect cognitive function.
The main research topics of ECMR are the investigation of liver cell biology and the more applied research line of drug design.
Research on four types of functionally active proteins - Copper proteins : hemocyanins (involved in dioxygen binding). - Thiol proteins: metallothioneins (metal detoxication and donation). - Protease inhibitors: alpha -2-macroglobulin homologues. - Regulatory proteins: cytokines (defencesystems against infection). Aim: to determine, after their isolation or possible induction, the composition and the primary to quaternary structure of these ...
Our research team studies spermatogenesis with a special focus on spermatogonial stem cells. Our current aim is to develop strategies in order to prevent infertility after gonadotoxic treatments. Fertility can be preserved by either limiting the loss of gametes and their precursors or by storing gametes and/or their precursors. Gonadotoxicity is an important side effect of cancer treatments. While adult men can bank their spermatozoa prior to ...
Correlations between echocardiographic, angiocardiographic and anatomical data in children with congenital heart malformations. Exercice tolerance studies in children before and after surgery for congenital heart malformations (gas exchange, determination of the ventilatory anaerobic threshold). (in collaboration with Dr. T. Reybrouck).
Laboratory for RNA Cancer Biology is a division of the Department of Oncology that fosters synergy in innovative oncological research. By creating a close link between bed and bench and by capitalizing on advanced technologies, our researchers aim to unravel key molecular mechanisms underlying the development and progression of cancer and to maximize opportunities to translate these findings into better clinical biomarkers, adaptive ...
The Laboratory of Lipid Biochemistry and Protein Interactions conducts high quality fundamental research, focusing on the role of peroxisomes in complex cellular processes (lipid metabolism, ROS/RNS metabolism, organelle dynamics and dysfunctions) in mammals and aims to provide insight in inherited and other human disorders linked to these organelles via cellular studies and mouse models.
The Laboratory of Lipid Biochemistry and Protein ...